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In the Spotlight

October 25, 2000

Ulcerative Colitis: Keys For Coping


By Michael A. Woo-Ming, MD, MPH
PersonalMD.com Medical Contributor

The large intestine is composed of your colon and rectum area, and is responsible for transporting waste, which needs to be expelled from the body. In a disease known as ulcerative colitis, the lining of the colon becomes inflamed which can lead to symptoms of pain and bloody diarrhea. Most people with ulcerative colitis can control their symptoms with medications, but in some surgery may be their only option.

What Is Ulcerative Colitis?


Along with Crohn's Disease, ulcerative colitis represents a type of disease known as Inflammatory Bowel Disease. It's commonly diagnosed in ages 14 to 38 years old, where about one hundred cases are seen in about 100,000 people. It's unknown what causes ulcerative colitis, but some researchers suggest an infection may trigger the disease. Ulcerative colitis also tends to run in families, with a 25 percent chance of getting the disease if a family member also has it.

Because ulcerative colitis appears to be more prevalent in industrialized countries, many doctors believe environment, especially the type of diet, is an important cause of the disease. High fat and high sugar diets have been associated (although not proven) with ulcerative colitis in longitudinal studies.

What Are The Symptoms Of Ulcerative Colitis?


The time course of ulcerative colitis usually presents itself as occasional flare-ups of symptoms, which can be quite severe, and remissions (symptom-free periods). The symptoms also tend to vary during the seasons, with worsening symptoms in the winter than the summer.

The most common symptoms include:
  • Rectal pain
  • Rectal bleeding
  • Fever
  • Abdominal swelling
  • Weight loss
  • Poor appetite

Other typical symptoms include pain while having a bowel movement and constipation. Ulcerative colitis can also affect other parts of the body outside the colon, such as arthritic symptoms, liver disease, skin rashes, and eye problems.

What Are The Treatments Of Ulcerative Colitis?

Medications can help calm flare-ups of ulcerative colitis. Corticosteroids, aspirin-like medications, and immunosuppressive drugs are most often used to reduce colon inflammation. Sufasalazine is an aspirin-like medication that is commonly used for treatment of mild attacks and helps maintain symptom-free periods. Prednisone is often used during attacks, available either as an oral medication or a suppository. Due to their powerful effects on the body, immunosuppresants such as azathioprine (Imuran) and mercaptopurine (Purinethol) are only used in severe attacks, or those in which a single medication can no longer control symptoms. Antibiotics may be used if bacterial infections accompany inflammatory bowel problems.

Surgery is the only curative option for ulcerative colitis, which is needed in about 20 percent of patients. Indications for surgery can include excessive bleeding, colon perforation, or to prevent colon cancer, which has been associated with ulcerative colitis. In a procedure known as a proctocolectomy, the diseased colon and rectum are removed, and an ileostomy (opening in the lower abdomen where the small intestine is attached) may be necessary to empty waste matter.

How Is Ulcerative Colitis Diagnosed?

Doctors will take a comprehensive history and physical, and then conduct laboratory and radiologic tests to determine if one has ulcerative colitis. Stool samples are usually taken, with the definitive test being a sigmoidoscopy or colonoscopy, where there is direct visualization of the colonic lining.

If diagnosed with ulcerative colitis, the most important aspect one can do is to keep oneself healthy through diet and exercise. Researchers suggest a diet plentiful in high proteins, fresh fruits and vegetables, with proper vitamin supplementation, can help minimize attacks, and allow ulcerative colitis patients to lead as normal life as possible.

For more information, please contact:

Crohn's & Colitis Foundation of America, Inc., 386 Park Avenue South. 17th Floor, New York, NY 10016-8804. (http://www.ccfa.org)



  

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