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In the Spotlight

December 07, 1999

Thyroid Disease in Adults: What Your Doctor is Looking for when Checking your Neck

By Michael Woo-Ming M.D., MPH
Personal MD.com
Medical Contributor

 

You're at the doctor's getting your routine annual physical. Everything's going fine then all of a sudden, the doctor exclaims "I think I found a lump on your neck, it's probably nothing.

But why don't we go ahead and order a TSH?" You shudder. TSH? What's that? TSH stands for Thyroid Stimulating Hormone. It's a screening marker test for thyroid disease, which affects millions of Americans, many of whom are not aware they have it.

Your Thyroid Gland

Your thyroid gland is located at the base of your throat, and among its functions includes regulating your metabolic rate. It consists of two lobes and surrounds your "Adam's apple". It secretes hormones that affect our weight and determine whether we are hot or cold.

It also directly affects our organs such as the heart. When there is an imbalance of how much thyroid hormone is produced, we can either fall in one of two ways: overproduction or underproduction. Thyroid stimulating hormone is responsible for coordinating these hormones.

Hyperthyroidism: Overproduction

Hyperthyroidism is the result of an overactive thyroid gland, and symptoms include a fast and irregular heart rate, nervousness, anxiety, weight loss, and a fine tremor. President George Bush and his wife Barbara (and even their dog!) were diagnosed with this condition, the common cause of which is known as Graves' disease.

Thyroid Stimulating Hormone (TSH) Test
Your doctor has ordered a TSH. What is it? Will it hurt? What do you have to do?

A TSH test is a blood test performed to evaluate the function of your thyroid gland. It measures the amount of thyroid stimulating hormone (TSH) in your blood. A change in the amount of TSH in the blood indicates a malfunctioning of the thyroid gland.

You'll be sent to a laboratory where a technician will draw a small amount of blood; you may feel a pinprick, but other than that, the test won't hurt. You don't have to do anything to prepare for the test. Just let your doctor know what medications you have been taking, including any over-the-counter (OTC) drugs such as aspirin, as some may interfere with the test results. You can eat or drink before the test; there are no food restrictions.

We believe Graves' disease occurs because our immune system is somehow altered into stimulating the production of more thyroid hormone. If not controlled, a condition known as exophthalmos may develop. This is when the eyes seem to bulge out from their sockets.

Treatment can include radioactive iodine, which suppresses the thyroid gland. Medications that can slow the heart rate may also be used. Finally, surgery to remove part of the dysfunctional thyroid gland can also have a successful result.

Hypothyroidism: Underproduction

Hypothyroidism (caused by a underproducing thyroid gland) is generally more common than hyperthyroidism, especially in middle-aged women. Hashimoto's disease is the most common form of primary hypothyroidism, with symptoms including lethargy, cold intolerance, fatigue, and hair loss. Viral and bacterial infections can also affect the thyroid gland, but usually temporarily.

People can also get nodules in their thyroid, which are mostly benign, although a physician will need to make sure that it's not cancer, usually by performing a thyroid scan or biopsy. A family history of thyroid cancer or previous neck irradiation will also increase your risk of hypothyroidism. Although generally benign, over time, hypothyroidism, if left untreated can develop into a condition called myxedema, which can result in fatigue, and eventual coma.

If you have hypothyroidism, most likely, your doctor will start you on synthetic thyroid hormone pills that you may need to continue for the rest of your life. Periodic blood work will be done to make sure the thyroid is functioning properly.

 

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