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In the Spotlight

The Crucial Need for Quick Action when a Stroke Occurs

By Lee Phillips M.D.
Personal MD.com
Advisory Board

 

There is a stroke about every minute and one person dies of stroke about every 3½ minutes, there are more than a half million strokes each year. A stroke, also called a "brain attack," occurs when blood flow to the brain is interrupted, and it is deprived of oxygen and other nutrients that it needs to function properly.

Strokes fall into two categories: those caused by blood-flow blockage and those caused by bleeding. An ischemic stroke, which occurs when a blood vessel in the brain or neck is blocked, is the most common stroke. Such blockages may form within a blood vessel of the brain or neck (thrombosis), may migrate to the brain or neck as a clot from another part of the body (embolism), or may result from severe narrowing of an artery in or leading to the brain (stenosis).

Less common is hemorrhagic stroke, in which a blood vessel bursts, causing bleeding into the brain or in the spaces surrounding the brain. If blood flow is not restored, those parts of the brain begin to die, causing affecting speech, vision, coordination, and thought. As the name "stroke" implies, it happens suddenly and often catastrophically; however, many strokes could be prevented by heeding the warning signs.

Warning signs are clues your body sends that your brain is not receiving enough oxygen. A stroke can occur suddenly and cause one or more symptoms and may disappear within minutes to hours. Call 9-1-1 immediately if you experience any of these symptoms, even if the symptoms go away and you feel fine again.

  • Numbness or weakness in one side of the body
  • Loss of vision
  • Difficulty speaking or understanding speech
  • Severe, sudden headache
  • Sudden weakness or numbness of the face, arm, or leg on one side of the body.

Other danger signs that may occur include double vision, drowsiness, and nausea or vomiting. Sometimes the warning signs may last only a few moments and then disappear. These brief episodes, known as transient ischemic attacks or TIAs, are sometimes called "mini-strokes." Although brief, they are signs of a serious condition that won't go away without medical treatment.

  • Stroke occurs in all age groups, in both sexes, and in all races in every country. It can even occur before birth, when the fetus is still in the womb. While anyone can have a stroke, there are factors that can place a person at higher risk.
    These include high blood pressure, smoking, an irregular heart rhythm, a prior stroke and diabetes. A physician can identify and help treat many of these risk factors.
  • High blood pressure, also called hypertension, is by far the most potent risk factor for stroke.
  • Cigarette smoking has been linked to the build-up of fatty substances in the carotid artery, the main neck artery supplying blood to the brain. Blockage of this artery is the leading cause of stroke in Americans.
    Also, nicotine raises blood pressure; carbon monoxide reduces the amount of oxygen your blood can carry to the brain; and cigarette smoke makes your blood thicker and more likely to clot.
  • Common heart disorders such as coronary artery disease, valve defects, irregular heart beat, and enlargement of one of the heart's chambers can result in blood clots that may break loose and block vessels in or leading to the brain.
    The most common blood vessel disease, caused by the buildup of fatty deposits in the arteries, is called atherosclerosis.
  • If you have had a stroke in the past, it's important to reduce your risk of a second stroke. Your brain helps you recover from a stroke by drawing on body systems that now do double duty. That means a second stroke can be twice as bad.
  • You may think diabetes affects only the body's ability to use glucose. But it also causes destructive changes in the blood vessels throughout the body, including the brain. Also, if blood glucose levels are high at the time of a stroke, then brain damage is usually more severe and extensive than when blood glucose is well controlled.

Stroke does not have to leave patients with permanent disabilities. The key to treating a "brain attack" is a speedy response by people experiencing strokes and their families. There is a "therapeutic time window" following a stroke during which proper treatment can restore blood flow and reverse brain damage once thought to be permanent, patients must be treated within three hours to benefit from this therapy.

Once a stroke is diagnosed, physicians can begin immediate treatment, lessening or even reversing the devastating effects of stroke, in many cases. Treatments for strokes are very specific, and depend upon the type, size and location of the blockage or disruption of blood flow in the brain. People are having an acute ischemic stroke caused by an artery blockage, can receive a powerful drug that dissolves brain clots.

Thrombolytic agents halt the stroke by dissolving the blood clot that is blocking blood flow to the brain. Recombinant tissue plasminogen activator (rt-PA) is a genetically engineered form of t-PA, a thombolytic substance made naturally by the body. T-PA has already been used effectively in people with heart attacks.

It can be effective if given intravenously within 3 hours of stroke symptom onset, but it should be used only after a doctor makes sure there is no bleeding in the brain by various tests, including a computerized axial tomography (CT) scan. Stroke patients who receive t-PA within 3 hours of their stroke were more likely to recover from their stroke with little or no disability.

It is unlikely that stroke will ever be eliminated completely. But medical weapons such as t-PA hold promise to at least help curb the disorder's destructive path. Because every minute counts in stroke treatment, stroke victims and those around them should learn to recognize stroke symptoms and seek help quickly, in order for this new treatment to have a benefit.

 

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