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In the Spotlight

November 2, 2000

Investigations: Pulmonary Function Testing


By Keith Petras, MD

PersonalMD.com Medical Contributor

Pulmonary function testing is used by physicians on a daily basis to evaluate and follow diseases affecting heart function, lung function, the effects of environmental exposures, for pre-employment physicals, and as an assessment of lung function for surgery. There are broad ranges of tests that physicians have available to them, however the most commonly used technique is referred to as Spirometry. Spirometry is commonly used to assess diseases affecting millions of individuals including asthma, bronchitis and emphysema. These tests are typically carried out in a physician's office and are neither invasive nor painful. In addition they can be repeated at intervals to assess trends in disease or response to therapy. In the following paragraphs the indications for, interpretation of and significance of Spirometry will be detailed.

The most common indication for pulmonary function testing is to evaluate a patient with unexplained shortness of breath or wheezing. Two very common diseases, asthma and emphysema, can be diagnosed and followed based on the results of Spirometry. In addition unexplained chest pain, poor oxygenation of the blood, or the effect of a non-lung disease on the lung can be evaluated. In addition patients undergoing surgery can be evaluated to determine how much lung reserve they have before surgery so physicians may take the necessary precautions when preparing for surgery.

Following are some essential steps that a patient needs to follow:
  • Take a full breath before the start of the test;
  • That the patient give maximum effort;
  • The test lasts at least 6 seconds;
  • There is no leaking of air around the mouthpiece;
  • That the patient does not cough or hesitate during the test.

Spirometry itself is very simple to perform. The patient begins by fully inhaling a breath of air to maximal capacity. Then he or she inserts a small piece of sterile tubing into the mouth and forms an airtight seal with the lips. The nasal passages are then clamped closed with a small rubber padded clip to prevent leakage of air through the nose. The patient then forcibly exhales all of the air in the lungs until they can no longer force any air out. The patient then takes a full inhalation without letting go of the mouthpiece. At the end of this inhalation a full breath cycle has been completed and the test is over. Typically the test is repeated three times and the results are averaged to provide the most accurate test result. In order to assure that the test is an accurate assessment of lung function the individual administering the test must insure that several criteria have been met.

The results from the test are then compared to "normal" individuals of the same age, sex, height and weight. (Testing individuals with no known heart or lung disease and using them as comparison models determine the "normal" values). It is this information that guides the physician to appropriate diagnoses and treatment, or in particular cases indicates the need for further testing.

The information that Spirometry provides can be quite valuable. The Spirometry machine records both the amount of air moved over a certain period of time, (referred to as flow rate), as well as the volume of air being moved by the individual during breathing. A graph of these variables tells the physician several things e.g. an individual with asthma has an obstruction in the airways of the lung caused by mucous and constriction of the lower lung passageways. This decreases the flow rate of the air being exhaled. For instance, imagine trying to blow air through a garden hose and then repeating the exercise by trying to blow air through a straw. The narrowness of the straw will prevent you from exhaling air rapidly and thus will increase the length of time to move the same amount of air through the hose. This is essentially what is happening inside of the lungs in individuals with diseases such as asthma and emphysema. It is this phenomenon that allows a physician to follow the severity of the lung disease. The more severe the lung disease, there will be more difficulty in forcing the air out of the lungs, just as the small diameter straw will make it more difficult to blow air.

As mentioned earlier the results of this testing are compared to "normal" controls. The further away an individual is from "normal" the more severe their disease. Once again asthma provides us with a good example. If an individual's results on Spirometry are >70 percent of normal they are considered to have mild disease. If however they have 60-70 percent of normal values they are considered to have moderate disease and so forth. By testing individuals over time the physician can determine if a particular disease is improving or increasing in severity and adjust treatment accordingly. In addition Spirometry can reveal several other indicators of lung function such as poor compliance of the chest wall or if the capacity of the lungs is decreased. All of these variables can be used to diagnose a broad range of diseases.

In conclusion, Spirometry is a simply non-invasive method of evaluating lung function that can be done in the office setting with no discomfort to the patient. In addition it can be repeated over time to reliably follow the course of a disease and direct treatment.


  

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