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Jelly beans used in pregnancy diabetes testing

NEW YORK, Dec 30 (Reuters Health) -- One of the challenges of pregnancy is the glucose tolerance test, where a sickeningly sweet sugary drink is used as part of a test for gestational diabetes. But Texas researchers have good news, especially for pregnant candy lovers -- jelly beans appear to be an excellent substitute for the very sweet sugar drink.

Women who consumed 28 jelly beans over 10 minutes were less likely to have side effects such as nausea, headache and dizziness than women who drank the sugar solution, according to a study of 136 pregnant women aged 18 to 40, published in the American Journal of Obstetrics and Gynecology.

Gestational diabetes can cause complications for both mother and fetus, so many women are tested for the condition in their second trimester. During the test, women rapidly drink a sugar solution and blood samples are collected afterwards to detect blood glucose levels.

In the study, Dr Michael E. Lamar and colleagues at Texas A&M University Health Science Center, set out to see if a standardized dose of 28 jelly beans providing 50 grams of simple sugar could be used as an alternative sugar source to the 50-gram glucose beverage currently used for the test.

The researchers found no significant differences between the two sugar sources in analysis of the blood glucose values after one hour. The group also found side effects such as nausea, headache and dizziness were reported less frequently by patients given jelly beans, and that women had a 3-to-1 preference for the jelly beans over the beverage.

But whereas the jelly beans work in the one-hour screening test for gestational diabetes, the authors do not advocate substituting jelly beans in the next stage of testing, the diagnostic 100-g glucose challenge test.

This 3-hour test is performed where the screening test is positive, suggesting that the woman may in fact have gestational diabetes. The authors explain that the diagnostic test requires the sugar drink because the solid nature of jelly beans and the complex carbohydrates contained in them may change the absorption rate of sugar and affect the test results.

Also, with only 5 cases of gestational diabetes mellitus diagnosed out of the 136 participants tested, Lamer would like to test the use of jelly beans in the screening test further before it comes into widespread use, to confirm that jelly beans prove equal to the 50-g glucose beverage for diabetes detection. "The suboptimal screening sensitivity documented in this study limits widespread clinical applicability," they conclude, "(but) the jelly bean challenge has immediate application for those patients unable or unwilling to drink the 50-g glucose beverage."


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