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Abnormal labor, mode of delivery tied to infant head injury

NEW YORK,(Reuters Health) -- Infants delivered through surgical procedures including forceps deliveries, vacuum extraction, and cesarean section, are at increased risk for bleeding in the head and brain, according to a study of nearly 600,000 infants.

Yet it's unclear whether the procedures alone are responsible for newborn head injuries. In Thursday's issue of The New England Journal of Medicine, researchers led by Dr. Dena Towner, of the University of California, Davis, report that the abnormal labor that prompts these delivery procedures may be to blame for some of the bleeds.

"The speculation is that something during labor causes the injury well before delivery, and it is not the mode of delivery that causes all bleeds," Towner told Reuters Health.

Her team found that among all infants born to first-time mothers in California between 1992 and 1994, one-third of deliveries involved one of these procedures. About 20 percent were delivered by cesarean section; 10 percent by vacuum extraction; and 3 percent by forceps. Compared with infants delivered naturally, all of these babies were 2.5 to 3.5 times more likely to suffer intracranial hemorrhage, depending on the procedure. Delivery using both forceps and vacuum extraction carried the highest risk -- more than seven times the risk. Other birth complications, such as breathing problems and temporary nerve damage, were also more common among infants delivered surgically.

But overall, complications were rare, with intracranial hemorrhage occurring in less than one percent of infants. And Towner and colleagues report that infants delivered by cesarean before labor had begun had no increased risk of intracranial hemorrhage. This, they concluded, suggests that the mode of delivery "is not necessarily the primary factor" in causing the injury. Towner noted that factors such as fetal distress and severe infection also cause intracranial hemorrhage. This bleeding, she noted, rarely leads to death, but is associated with cerebral palsy and developmental delays.

When labor is unsuccessful in achieving delivery, doctors must choose between performing a cesarean section or an assisted vaginal delivery, Dr. Thomas J. Benedetti, of the University of Washington in Seattle, notes in an editorial published with the report. This study's most important finding, according to Benedetti, is that the risk for intracranial hemorrhage appears to be no higher with assisted vaginal delivery than with cesarean.

In 1998, Benedetti notes, the Food and Drug Administration advised doctors to perform vacuum extraction only in certain instances. This came after the agency received reports of 12 deaths and nine serious injuries during vacuum extraction over the previous four years.

This study, Benedetti writes, suggests that there is an "apparently irreducible" number infant injuries due to abnormal labor, rather than the mode of delivery. However, he notes, these findings should be interpreted with caution, and obstetricians must "gather all the available data" to be able to decide whether a mode of delivery will be successful.


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