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Skin cancers often found late in males, smokers, singles

NEW YORK, Jul 25 (Reuters Health) - Previous research has shown that Medicaid patients are almost five times as likely as those with commercial insurance and about twice as likely as uninsured individuals to have a late diagnosis of the deadly skin cancer, melanoma. Now new research shows that certain sociodemographic factors such as sex or marital status may also be linked to a late diagnosis of the condition.

"The prognosis of malignant melanoma is heavily dependent on the stage at which it is detected," write researchers led by Dr. Daniel J. Van Durme from the department of family medicine at the University of South Florida. "Therefore, understanding the determinants of late-stage melanoma diagnosis is an important cancer-control objective."

In this follow-up to their previous study which reported the effect of insurance payer on cancer stage at diagnosis, Van Durme and his colleagues hypothesized that age, sex, marital status, education, income, residence--rural vs. urban--and smoking status would all be associated with a risk of late-stage diagnosis of melanoma. A review of almost 1,900 melanoma cases occurring in Florida during 1994-1995 revealed that "late-stage diagnosis was more common among patients who were male, unmarried, and smokers and resided in communities with low median income and education levels," the authors write in the July issue of Archives of Family Medicine.

The authors note that their research is consistent with previous studies that also identified men as being "less likely than women to identify their own melanoma." This is perhaps because men are also reportedly less likely to undergo either self-screening or physician screening.

However, individuals who engage in self-screening may not easily detect less visible lesions, Van Durme's research suggests. Marital status, therefore, may prevent late-stage diagnosis since spouses have been identified as "the third most common person" to detect many melanomas. "This finding suggests that physician surveillance of melanoma is especially important for unmarried patients," the authors comment.

Furthermore, cancer patients who live in areas where the median educational level was high school or less as well as those with a lower socioeconomic status--a median household income of $15,000 - 25,000--were more likely to have a later diagnosis, according to the research. "Patients with a lower socioeconomic status are less likely to undergo either self-screening or physician screening," Van Durme's team explains. In addition, these individuals may have a decreased awareness of and knowledge about the skin cancer, the authors state.

Yet, despite these other factors, the authors found smoking to be the greatest predictor of a late-stage diagnosis of melanoma. They hypothesize that smoking may be associated with "less active skin surveillance," consequently, melanomas would not be detected until a late stage.

The authors acknowledge several limitations of their study such as the fact that their data was limited to melanoma cases in Florida, "which may not be representative of other diseases or other parts of the country." Yet, Van Durme and his colleagues stress the need for physician awareness of these risk factors and they urge a "more conscientious" screening of high-risk patients. In addition, public education efforts recommending increased "self-surveillance and checking the partner's skin" should be targeted to patients with a higher risk of melanoma, the authors suggest.


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