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Study Says Quitting Snuff Helps Avert Cancer

By Nicole Foy, San Antonio Express-News

SAN ANTONIO -- For those thinking about giving up the smokeless tobacco habit, here is some good news: An Air Force study says most pre-cancerous changes in the mouth caused by snuff and chewing tobacco disappear within weeks after quitting.

The study, published this month in the Journal of the American Dental Association, illustrates the importance of giving up smokeless tobacco products before such lesions become cancerous, said the lead author of the study, Lt. Col. Gary Chad Martin, a dentist who studied basic military trainees at Lackland Air Force Base in San Antonio.

``I wish this would have shown that there was a high occurrence of pre-cancerous lesions and it would have scared the heck out of everybody,'' Martin said. ``Instead, it showed how fortunate we are that the body is able to heal itself. But it takes quitting before the process starts.''

Other studies have concluded that the risk of getting oral cancer is up to four times greater for smokeless tobacco users than non-users. The latest study demonstrated that such products, especially snuff, are associated with pre-cancerous lesions in the mouth lining known as leukoplakias.

Leukoplakia is a disease characterized by white, leathery patches on the tongue or gum. The patches can become irritated by the tobacco juice.

Martin said he chose to study military trainees because they are forbidden from using tobacco products during the six weeks of basic training. The situation provided a controlled setting in which to study the benefits of quitting smokeless tobacco products.

At the beginning of basic training, Martin performed oral examinations on 3,051 male trainees at Lackland. About 10 percent -- or 302 trainees -- reported they were regular users of snuff or chewing tobacco. Of those users, 119 had leukoplakia.

Once training ended, these trainees were re-examined, with the exception of 10 young men who previously had been discharged. Of the 109 remaining, the lesions of 106 trainees had completely disappeared.

The three trainees whose lesions remained were evaluated further and the patches were found to be benign, or not cancerous.

``I keep stressing that there was clinical resolution demonstrated here, which doesn't preclude the possibility that these products could have done some residual damage at an even more basic, DNA level,'' Martin cautioned.

Other studies have indicated that somewhere between 3 and 6 percent of oral leukoplakias go on to become cancerous, Martin said.

Martin, who was a dental resident at the University of Texas Health Science Center during the study, now is an assistant professor at the Center for Oral Health Studies at the Uniformed Services University of the Health Sciences in Bethesda, Md.

Martin said he's noticed an increasing trend of cigarette smokers opting instead for smokeless products to try and cut their habit.

``The problem is, as we have deglamorized cigarette smoking, people have switched over to snuff because it is more discreet,'' he said. ``But it carries some of the same health risks and can be very damaging to the lining of the mouth.''

Snuff and chewing tobacco can cause cancer and a number of non-cancerous oral conditions. It can also lead to nicotine addiction and dependence.

Martin's former professor, who contributed to the journal article, said the study offers hope for young males who want to quit smokeless tobacco products.

``This points to the value of stopping,'' said Dr. John Brown, chairman of community dentistry at the University of Texas Health Science Center. ``The earlier you stop, the better chance you have to avoid the problems that can come along with it.''


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