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Breath tests may help diagnose schizophrenia

EDINBURGH, Jul 05 (Reuters) - Breath tests and skin patches could become standard tools to help doctors diagnose and treat schizophrenia, researchers said on Tuesday.

Scientists at the Highland Psychiatric Research Foundation in Inverness, Scotland, tested the breath of 90 patients and a control group for abnormally high levels of certain gaseous particles which may be linked to the disease. "Diagnosis is always one of the big problems with schizophrenia," said Dr Marion Ross, a biochemist working on the project. "This is only preliminary research but we are getting some promising results," she told Reuters at the Royal College of Psychiatry conference.

The experiments showed dramatically increased levels of ethane and butane in the breath of diagnosed schizophrenics. The number of butane particles in the exhaled breath also appeared to bear a correlation with the severity of the disease.

Separate trials of skin patches showed that the skin of patients diagnosed with acute schizophrenia turned a livid red when a specially treated patch was applied, while that of unafflicted patients remained unchanged. Moderate schizophrenics displayed a moderate reaction, leading scientists to believe the technique could be used as a litmus test for how well a patient is responding to treatment.

Another advantage of both non-intrusive tests is that they present sufferers with visible proof of the disease. "One of the main problems with schizophrenia is patients seldom believe they have the disease. It's not like diabetes where you can just shown them results of a blood test," Ross said.


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