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Men Reluctant To Discuss Prostate Cancer, Seek Treatment

At age 47, Damon Harris had three Grammys, two American Music Awards, nine gold records, including ``Papa Was a Rolling Stone,'' and prostate cancer that had already spread to his lymph nodes.

A member of the Motown vocal group The Temptations from 1971 through 1975, Harris thought he was too young for prostate cancer, a disease whose strongest risk factor is age, striking most often in the late 60s and early 70s. But he is African-American, which increases the risk of prostate cancer by at least 50 percent. And his father died of the disease when he was 62.

When Harris' cancer was discovered in January 1998, it was too late for many choices.

``My only option at that point was hormone therapy to suppress the testosterone that was feeding the tumor,'' Harris, 49, said in a recent telephone interview.

Harris ignored symptoms such as frequent urination and pain in his lower back and hips, attributing them to the fact that he was exercising heavily and drinking a lot of water. He cut his fluid consumption to ``cure'' the problem and almost forgot about it until he noticed blood in his urine.

``Men don't talk about the symptoms because of what they might mean,'' he said. ``The side effects of the necessary treatment are a big issue. The sexuality concerns are a lot like those with mastectomy for women. My father had a radical prostatectomy, and he just wouldn't talk about it at all.''

Harris said that despite all the warning signals, he never even considered that he might have prostate cancer.

``When I was diagnosed, I realized that I had had the symptoms for at least five years,'' he said. ``But I didn't do anything about it, and I didn't talk about it. Nobody does.''

Which is exactly why this year the National Men's Health Foundation has chosen prostate cancer as the focus for Men's Health Week. In 2000, about 180,400 American men will learn they have cancer of the prostate, a walnut-size gland that wraps around the base of the urethra and produces the fluid that transports sperm.

An estimated 31,900 men will die of prostate cancer in this country this year, said Tracie Snitker, spokesperson for Men's Health Week.

For black men, the statistics are worse: African-American men are at least 50 percent more likely to develop prostate cancer and twice as likely to die from it as men of any other racial or ethnic group in the United States.

But talking about the disease may prolong, and even save, lives.

Major advances in prostate surgery and radiation therapy over the past five to 10 years mean those who detect the cancer early enough are likely to enjoy longer lives with fewer, less severe side effects.

For men like Harris' father, just one generation ago, treatment almost always resulted in impotence and even incontinence.

And for men like Harris, whose diagnosis was made only after it had spread from the prostate, there is no cure. Harris' hormone injections help to control the spread of the disease and have brought it into remission. But the treatment has caused weight gain, accelerated heart disease and angina, and has greatly reduced his sexual drive.

Today, though, for those who detect prostate cancer at its early stages, while it is still confined to the gland, a new nerve-sparing prostatectomy surgery and two new forms of radiation therapy are options offering fewer side effects and higher five-year cure rates.

Management of early-stage prostate cancer is improving, and death rates are dropping every year, said Dr. Hugh Lamensdorf, a Fort Worth urologist and former president of the Tarrant County Medical Society.

Whether surgery or radiation is a better option for men with localized cancer of the prostate is a matter of debate among doctors, and though at least one clinical study has shown the procedures to have competitive five-year success rates, longer-term rates are still unknown.

``We urologists are convinced surgery is the best treatment,'' Lamensdorf said.

Nerve-sparing radical prostatectomy protects the nerves wrapped around the outside of the prostate to preserve sexual function. It was developed in the early 1980s by Dr. Patrick Walsh at Johns Hopkins Hospital in Baltimore to cure the cancer while preserving sexual potency. The treatment is now widely available, Lamensdorf said.

``In surgery, we've lowered the risk of incontinence dramatically and now have methods to spare the nerves,'' Lamensdorf said. ``It depends on the age of the patient, but for those under 60, the success rate in preserving sexual function may be as high as 80 percent. Our main job is to cure the cancer - if at all possible without compromising sexual function.''

New twists on radiation treatment for prostate cancer include precisely targeted external beam radiation and interstitial brachytherapy, an internal radiation therapy that uses small, radioactive pellets (each about the size of a grain of rice) that are implanted directly into the prostate.

Brachytherapy, which was developed 15 years ago, is the easiest on the patient, doctors acknowledged. It is the least likely to cause impotence or incontinence and can be done on an outpatient basis.

``There is a lot more enthusiasm for it than we have statistics to support,'' Lamensdorf said. ``Results look good so far, but doctors are not ready to abandon surgery.''

Results from one 10-year study, reported in U.S. News & World Report, show that 85 percent of those treated with the pellets no longer show signs of the cancer.

In applying external beam radiotherapy, radiologists now use a computerized model that allows them to pinpoint the radiation so the dose can be increased and applied directly to the tumor without increasing complications.

Treatment for prostate cancer has improved because early detection has greatly increased, thanks to education efforts and the PSA (prostate-specific antigen) screening test, a simple blood test used in conjunction with the standard digital rectal exam.

Today, 79 percent of all prostate cancers are discovered in the local and regional stages. The five-year survival rate for patients whose tumors are diagnosed at these stages approaches 100 percent, according to the American Cancer Society. Over the past 20 years, the survival rate for all stages combined has increased to 92 percent, from 67 percent.

And it couldn't have happened if men hadn't finally started talking about it.

As Harris said, ``You can't cure something you don't know you have, and you're not going to even suspect prostate cancer if nobody ever talks about it.''


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