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C-section best for women with cervical cancer

By Suzanne Rostler

NEW YORK, Jun 13 (Reuters Health) - Women who are diagnosed with cervical cancer during pregnancy seem to do better if they deliver by cesarean section, a new report suggests.

The risk of being diagnosed with the cancer in pregnancy is rare--occurring in 0.05% of all pregnant women--but cervical cancer is still the most common malignancy associated with pregnancy, according to the report in the June issue of Obstetrics and Gynecology.

In a study of 83 women diagnosed with cervical cancer either during pregnancy or shortly after giving birth, researchers found that the cancer was more likely to recur in either the pelvis or a distant site such as a lung after a vaginal delivery than after a cesarean section. In an interview with Reuters Health, study co-author Dr. Joel Sorosky from the University of Iowa in Iowa City explained that "tumor cells may be spread locally and distantly by the dilation of a cervix with cancer."

The cancer had no impact on the newborns regardless of the method of delivery, Sorosky added. The women--56 who had cancer diagnosed during pregnancy and 27 whose cancers was diagnosed within 6 months of giving birth--were compared with women who were diagnosed with cervical cancer at least 5 years after giving birth.

Among those diagnosed with cervical cancer 6 months after delivery, 14% of patients who had a cesarean section had a cancer recurrence, compared with 59% of women who delivered vaginally. "Our study suggests that vaginal delivery is associated with poorer survival for both those diagnosed prenatally and postpartum," the authors conclude. The researchers add that the findings highlight the need for cervical screening in the early stages of pregnancy. Indeed, women diagnosed with cervical cancer late in their pregnancy or after they had given birth tended to have cancer that had already spread.


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