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Bypass prevents heart deaths in diabetics

Diabetics who have a heart attack are much more likely to survive if they have previously had bypass surgery than if they have had another procedure called balloon angioplasty, according to a new report.

When a vessel that delivers blood to the heart becomes blocked, options for restoring blood flow to the heart include bypass surgery and a procedure called balloon angioplasty. Bypass surgery involves taking veins, and sometimes arteries, from other parts of the body and grafting them from the aorta to the coronary artery to bypass the blocked vessel. During angioplasty a balloon-tipped catheter is threaded into a blocked artery and inflated, flattening fatty plaques against the artery wall.

Recently published study findings had already shown that people with diabetes survive longer after having bypass surgery than after angioplasty. But why this should be the case was not clear. To find out why, a team of researchers led by Dr. Katherine M. Detre, of the University of Pittsburgh, Pennsylvania, reanalyzed the data.

In the study, 8% of people with diabetes and 4% of those without the disease had a heart attack. In people who did not have diabetes who had a heart attack, the effects of angioplasty and bypass surgery were roughly the same.

But bypass surgery provided "dramatic" protection to diabetics who had a heart attack. Specifically, just 17% of diabetics who had bypass surgery died after a heart attack, compared with 80% of those who had angioplasty. "Treated diabetic patients who had coronary bypass surgery are more likely to survive a heart attack than diabetics who had angioplasty," Detre told Reuters Health in an interview. She said that bypass surgery "provides a protective effect for patients who experience heart attack."

Detre pointed out that diabetics who had bypass surgery and then had a heart attack were about as likely to survive the heart attacks as people without diabetes. "It was as if they didn't have diabetes," she said.

In an editorial that accompanies the study, Dr. Steven M. Haffner, of the University of Texas Health Science Center in San Antonio, writes that patients with diabetes who undergo angioplasty should also be treated aggressively for heart risk factors and for their diabetes. He notes that several types of medications, including aspirin, beta-blockers and ACE inhibitors have been shown to help prevent heart attacks.


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