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Most people unaware that wart virus is a major cancer risk

NEW YORK, Feb 17 (Reuters Health) -- It is one of the most common sexually transmitted diseases in the United States, but 70% of Americans 18 and older said they have not heard of the human papillomavirus (HPV), according to results of a survey by the Kaiser Family Foundation, a nonprofit agency based in Menlo Park, California.

HPV, which infects more than 5 million people each year, can cause genital warts or can be completely symptom-free.

There are more than 70 different types of HPV that can cause warts on the hands, feet, lips, tongue and genitals. About 13 of the viruses that are sexually transmitted have been linked with genital or anal cancers in men and women. However, most people infected with HPV never develop cancer.

According to the survey of more than 1,000 people, only 41% of those surveyed knew that the virus can lead to cervical cancer and 42% knew that it could cause genital warts. Only 5% said they had discussed HPV with their healthcare provider. About half knew that the virus is not curable, the survey found.

"HPV can cause warts and cervical disease in some people but they are a minority. The good news is that no one needs to die of diseases caused by this virus," said Dr. J. Thomas Cox, executive medical director of the American Social Health Association.

In most cases, genital warts do not develop into cancer, Cox said. "The anxiety surrounding HPV is not necessary," said Cox, who presented the results of the survey at a press briefing here on Thursday. Over time, most people probably suppress the virus to the point where it is no longer detectable or contagious, Cox said.

If a woman is at risk for cervical cancer, she doesn't necessarily need to be tested for HPV. A routine Pap test in which a swab is taken from the cervix during a gynecological exam, transferred to a slide and examined under a microscope can determine if cells are undergoing precancerous changes that need to be treated.

Last year, the Food and Drug Administration (FDA) approved a DNA test that can identify the exact type of the virus. The test can detect about 90% of cervical cancer cases, compared with about 70% to 80% of cancer cases detected through the Pap test.

However, the DNA test is not yet widely available in the US. It is not clear whether all women should receive DNA screening for HPV, which occurs in many women but causes cancer in a minority, or if the test should target specific groups of women.

For example, older women, sexually active teenagers and women in developing countries who do not get regular Pap tests or do not have access to basic medical facilities may benefit from the DNA test. Researchers said more studies are needed to determine if widespread testing for HPV is economically feasible and if it can lower rates of cervical cancer.

The American Cancer Society estimates that during 2000, about 12,800 cases of invasive cervical cancer will be diagnosed in the US and about 4,600 women will die from the disease.


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