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Guidelines aim to prevent Lyme disease in children

NEW YORK, Jan 13 (Reuters Health) -- The American Academy of Pediatrics has issued new guidelines on preventing Lyme disease in children.

Lyme disease is caused by a bacteria spread through the bite of ticks carried by wild animals such as deer. About 9 out of 10 cases of Lyme disease are reported from 13 states along the northeastern and mid-Atlantic seaboard and in the upper north-central region of US, with the bulk of cases among children aged 2 to 15 and those over age 30.

But the Lyme disease vaccine has not been approved by the Food and Drug Administration (FDA) for use in individuals under age 15.

"Lyme disease is so geographically clustered that recommendations (for prevention in children) are based on risk... We are hampered at this time by the lack of approval (by the FDA) for the Lyme disease vaccine for persons under the age of 15," AAP former chair of the Committee on Infectious Diseases, Dr. Neal A. Halsey, told Reuters Health in a telephone interview.

Halsey, of Johns Hopkins University in Baltimore, Maryland, and associates are currently conducting efficacy trials of the Lyme disease vaccine in children. "We've identified no problems to date. We hope to present this data to the FDA in April. Hopefully, the FDA will extend approval down to children as young as age 4. That might happen by the end of the year, and we hope it will happen before the next Lyme disease season in 2001."

The vaccine provides effective protection against Lyme disease, especially the asymptomatic form, Halsey said. "But people can't forgo the usual preventive measures," he added.

"The most important measure to take is examination of children (after being in tick-infested areas)," Halsey said. Finding ticks is important because the tick needs to be attached for at least 36-48 hours before disease transmission occurs, he noted.

And in the report published this month in the Academy's journal Pediatrics, child health experts warn against the use of prophylactic antibiotics for children bitten by ticks. "We do not recommend prophylactic antibiotics," Halsey stated. "The risk after tick exposure is very low...There can be more harm done with the overuse of antibiotics in the attempt to prevent Lyme disease."


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