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In the Spotlight

October 07, 2000

Coming To Grips With Gout


By Michael Woo-Ming, MD, MPH

PersonalMD.com Medical Contributor

You've been diagnosed with gout, so what exactly does that mean? Long known as a disease of the wealthy, we know gout is when you have too much uric acid in the body. Uric acid buildup can occur, without any symptoms for years, culminating in painful inflammation of joints, most typically of the feet and big toes. With proper prevention however, gouty attacks can be minimized by diet and medications.

The Culprit: Uric Acid

There are many conditions that can cause an increased uric acid level. They include:
  • Obesity
  • Excessive alcohol consumption
  • Dehydration
  • Eating purine-containing foods
  • Certain medications for high blood pressure (diuretics)
  • Certain cancers and red blood cell disorders

Uric acid is a by-product of our natural chemical processes when we break down food or build up body tissues. The accumulation of uric acid can occur in two ways: Either our body produces too much of it, or more commonly, our kidneys do not eliminate enough uric acid. Too much uric acid in the blood is known as hyperuricemia allowing the formation of uric acid crystals in joints, causing the characteristic inflammation known as acute gouty arthritis.

Interestingly, most people who have high uric acid levels in their blood never get gout. And in contrast, there are a few unlucky who have gout even with normal uric acid levels and in such cases the cause is still unknown. Gout also tends to run in families.


Symptoms Of Gout

The typical presentation of gout is a painful big toe, and usually affects only one or two joints at the most. The inflammation can severely limit the movement of the joint. Uric acid deposits known as tophi may also develop under the skin. They are generally painless (but unsightly) and can be found on the fingers, toes, elbows, and on the outside of the ears. The acute attack will usually subside in a week if no treatment is initiated. Uric acid kidney stones can also occur causing the typical presentation of kidney stones, which is symptoms of nausea, vomiting, and abdominal pain.

Treatment Of Gout

When a suspected gout attack occurs, the first step is to see your doctor. Blood work such as checking a uric acid level will often be drawn, and if the diagnosis is still in question, fluid aspiration to look for uric acid crystals in the affected joint may be performed. To treat the arthritis and pain, anti-inflammatory medications such as indomethacin and colchicine are often prescribed, and if a severe attack, prednisone may be warranted.

For those with a history of gout attacks, taking a daily medication such as probenecid or allopurinol will help decrease the amount of uric acid in the body.

Prevention Of Gout

The key to prevention is limiting the factors that can cause higher uric acid levels. Historically, keeping your diet low in purine-containing foods has been recommended to decrease the frequency of gout attacks. These include:

  • Liver, sweetbreads, and beef tongue
  • Red meats
  • Peas, beans, and lentils
  • Shellfish and scallops

It is just as important to lose weight if obese, and drink plenty of fluids while limiting the alcohol consumption. If you think you may be at risk for gout, it is best to discuss this with your primary doctor for the best way to manage and treat this problem.



 

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