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In the Spotlight

PEPTIC ULCER DISEASE AND ACID REFLUX

By Adam Brochert, M.D.
PersonalMD.com, Medical Contributor

 

Peptic Ulcer Disease (PUD) and Acid Reflux (known as Gastroesophageal Reflux or GERD) are two of the most common known digestive disorders. Together, they affect over one-third of the U.S. population. Fortunately, the majority of those who suffer with these conditions can be treated and go on to lead normal, healthy, productive lives.

Peptic Ulcer Disease (PUD)

We all have about a 10% chance of developing PUD at some time during our lives. There are certain risk factors, however, that make it more likely. Males get the disease more frequently than females and genetics are thought to play a role. Other common risk factors include aspirin use (and other non-steroidal anti-inflammatory medications such as ibuprofen and naproxen, but not Tylenol), a specific bacterial infection (the bacteria is called Helicobacter pylori or H. pylori), cigarette smoking and alcohol abuse. Stress, as you may have heard from your mom, can also be a contributing cause.

There are two major types of ulcers and their symptoms can be different. The first is a duodenal ulcer. You may know that the duodenum is the first portion of your gut that food enters once it leaves the stomach. This is the most common location for an ulcer, and accounts for about 75% of cases. The most common symptom is burning epigastric pain, which usually comes on 90 minutes to 3 hours after a meal. The pain often comes on at night and may be relieved by eating and antacids.

The second type of ulcer is a gastric ulcer. This disease will also give you epigastric pain, but the pain is usually unrelated to food and may actually be made worse with eating. The treatment for both of these ulcers is similar.

First, avoid aspirin / other non-steroidal anti-inflammatory drugs, smoking and alcohol. Second, physicians will commonly prescribe antacids or medications to decrease stomach-acid secretion (drugs like Pepcid, Tagamet, Axid, Zantac and others). Often, your doctor will also prescribe a brief course of antibiotics to eliminate a probable H. pylori infection in your gut. These simple measures will allow most patients to get back to an active, pain-free life!

Acid Reflux or Gastroesophageal Reflux (GERD)

Up to 33% of all American adults will experience at least one episode of heartburn per month. This aggravating symptom is caused by GERD. Although the exact etiology of GERD is unknown, it is thought to be due to inappropriate relaxation of the muscle which acts as a barrier between the stomach and the esophagus. This muscle normally protects the esophagus (the tube that connect your throat to your stomach) from the large amount of acid in your stomach. When this muscle doesnt stay closed tightly, acid from the stomach can rise up into the esophagus and cause heartburn.

Risk factors for heartburn include obesity, pregnancy, smoking and a common condition known as hiatal hernia (the stomach sits a little higher in the body than usual). Because GERD is so common, many who get the disease have no risk factors at all. Symptoms are commonly aggravated by lying down and eating certain foods and relieved by sitting up. Treatment is often done in steps.

First, patients are asked to elevated the head of their bed and to make certain dietary changes. Coffee, citrus juices and spicy foods are notorious culprits and should be avoided. Avoidance of food for at least 3 hours before going to bed has also been shown to decrease episodes of heartburn.

Antacids are also commonly prescribed to relieve symptoms. In addition, your doctor may prescribe acid-reducing medications just like the ones used for peptic ulcer disease (e.g. Pepcid, Zantac, Axid and others). As in PUD, these simple measures are usually enough to return people to their normal lives!

Other Tests For PUD and GERD

Your doctor may want you to go through additional testing with either one of these conditions, depending on your situation. One common test is a barium swallow, where you will be asked to drink a liquid substance and then have an x-ray taken. Another test is called endoscopy and involves placing a small tube into your esophagus and stomach. A camera on the end of the tube allows the physician to see inside your stomach. Both tests are quite common, low-risk and painless. They can be important in monitoring your condition and making sure there are not more serious disease processes taking place.

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