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By
Lee Philips M.D.
PersonalMD.com
Advisory Board
Did you know the most crucial stages in a babys development occur
before a woman may realize she is pregnant? Both you and your baby
need adequate folic acid to prevent neural tube defects.
The critical time for the development of the brain and spinal column
is in the first four weeks of pregnancy. The tricky part
is that over half of all pregnancies are unplanned and these defects
occur in the developing fetus before most women know they are pregnant.
That's
why it is important that all women of child-bearing age (15-45)
to get 400 micrograms (.4 mg) of folic acid daily. Many women consume
much less than 400 micrograms of folate a day. Even if you' re not
planning to get pregnant right now, taking folic acid reduces the
chance of the baby having a birth defect of the brain or spinal
cord, if you have an unplanned pregnancy. Some women don't realize
they are expecting until it is too late for supplements to do much
good.
What
is folate?
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spinabifida:
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| a
congenital cleft of the spinal column with hernial protrusion
of the meninges and sometimes the spinal cord |
Folate
is a B vitamin found in a variety of foods and the synthetic form
known as folic acid is found in vitamin and mineral supplements.
Folic acid is needed to synthesize DNA which is the building block
for for all new cells of the body, and thedaily requirement increasesduring
pregnancy. Folate is especially critical in the first weeks of pregnancy,
when the neural tube is developing, which later forms the spinal
cord and brain. With inadequate amounts of folate birth defects
such as spina bifida and anencephaly may occur.
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anencephaly:
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| congenital
absence of all or a major part of the brain |
There
are about 2,500 with spina bifida and anencephaly are born each
year in the United States. The recommended daily dosage of folic
acid can reduce a baby's risk of some types of birth defects by
50 percent.Some women are at a higher risk for having babies with
these birth defects. If you have diabetes, take anti-seizure drugs,
have a family history of neural tube defects, or have already had
a pregnancy affected by neural tube defects, talk to your doctor
before you become pregnant. Women who may need more folic acid include
drug or alcohol users, smokers, women on birth control pills, and
women who diet and don't eat well-balanced meals.
Neural
Tube Birth Defects
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neural
tube:
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| the
hollow longitudinal dorsal tube that is formed by infolding
and subsequent fusion of the opposite ectodermal folds in the
vertebrate embryo and gives rise to the brain and spinal cord
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There
are two main kinds of neural tube defects reduced by adequate folate
intake, anencephaly and spina bifida. The most serious neural tube
defect is anencephaly. The baby is born without part of its skull
and brain, and dies soon after birth. The most common neural tube
defect is spina bifida.
The
bones of the spinal column that surround the spinal cord do not
close properly during the first 28 days of pregnancy. A portion
part of the baby's spinal cord remains outside the body and forms
a sac protruding on the infant's back. Doctors must repair the opening
of the spine shortly after birth or the child will die. Depending
on the severity of spinal cord damage there will be varying degrees
of paralysis and incontinence. Many children require a series of
operations and other treatments throughout childhood. To help
prevent this type of birth defect, it is very important for women
who are or may possibly become pregnant, take adequate ammounts
of folate.
Some
Good Sources of Folate
Women
have options for getting the needed folate. Leafy green vegetables
and lettuce; citrus fruits and juices: beans and peas; broccoli
and asparagus; and liver are great natural folate sources. Folate's
potential to reduce the risk of neural tube defects is so important
that the FDA requires food manufacturers to add folic acid to enriched
grain products such as flour, bread, cereal, pasta, rice and waffles.
Some of the natural folate in non-whole-grain products is lost in
the process of refining whole grains. Whole-grain products do not
have to be enriched because they contain natural folate. By following
the USDA Food Pyramid Guide, which suggests 3 to 5 servings of vegetables,
2 to 4 of fruits and 6 to 11 servings of grains daily, women can
easily get 400 of folate in their diet. Taking a multivitamin
that has 0.4 mg of folic acid is another way of getting the recommended
amount.
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FOLATE FACTS:
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| Folic
acid come from the word foliage because it is found in high
concentrations in green leafy vegetables. |
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| Folate
also known as folic acid is a water soluble B vitamin. |
| Americans
get plenty of the B vitamins, with the exception of folate. |
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| Nutrition
information on food and vitamin labels can help women get enough
folate, which is 400 micrograms a day before pregnancy. For
pregnant women, the daily requirement jumps to 800 micrograms. |
| Because
folate is a water soluble vitamin, it is lost in cooking water. |
| Eat
more raw vegetables, salads, spinach, broccoli. |
| To
prevent folate loss cook vegetables in a small amount of water
for the shortest amount of time, or steam, microwave or stir-fry.
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| Store
your fresh fruits and vegetables in the refrigerator. |
| The
longer they are fruit and vegetables are stored the more folate
that is lost. |
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| Babies
conceived in the winter are more likely to be born with spina
bifida, perhaps because of the lack of fresh fruits and vegetables
available in the winter months. |
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