An
electrical pacemaker implanted under the collar bone with wires that lead not
down to the heart, but upwards to finally wrap around the vagus nerve. Once in
place, an electric pulse is generated and relayed to the brain to control seizures.
It is not fully understood how the electrical impulses reduce seizure activity.
But it is thought that the electrical impulses override the abnormal brain activity
responsible for seizures.
In
a normal brain millions of tiny electrical charges pass from nerve cells in the
brain to control all parts of the body. In patients with epilepsy, this normal
pattern is interrupted by sudden and unusually intense bursts of electrical energy,
which may briefly affect a persons consciousness, bodily movements, or sensations.
Epilepsy
occurs when nerve cells in the brain fire electrical impulses at a rate of up
to four times higher than normal. This causes a sort of electrical storm in the
brain, known as a seizure. A pattern of repeated seizures is referred to as epilepsy.
Approximately 1.7 million Americans have epilepsy. Epilepsy may result from a
brain injury before, during, or after birth; head trauma; poor nutrition; some
infectious diseases; brain tumors; and some poisons. However, in many cases the
cause is unknown. Medication controls seizures for the majority of people and
they are healthy and able to live full and productive lives.
On
the other hand, at least 200,000 Americans have seizures that cannot be adequately
controlled by drugs or surgery or have unbearable side effects from medications.
Instead of being controlled, refractory epilepsy , characterized by frequent and
violent seizures often controls the life of a patient. Their lives are devastated
by frequent, uncontrollable seizures.
| Epilepsy: |
| What
is epilepsy? Epilepsy
is a tendency to have recurrent seizures. Seizures occur when there is an imbalance
in the electrical activity of the brain. Click
here to read more about Epilepsy |
Vagus
nerve stimulators offer people with uncontrolled seizures a new type of treatment,
and does not involve surgery on the brain. During a two hour out-patient procedure
the nerve stimulator is implanted in the patient. Then the nerve stimulator is
programmed to deliver intermittent electrical pulses on a regular basis: 30 seconds
on 5 minutes off; for example, 24 hours a day regardless of seizure activity.
A stimulus can be felt in the neck, when an impulse is generated.
The
vagus nerve is a "super highway" of sorts, carrying information in two directions,
from the body's internal organs to the brain and from the brain to the body again.
The vagus nerve controls the heart rate, lungs, vocal cords, windpipe, and digestive
system. Because of this side effects that can occur when the device delivers a
shock are cough, hoarseness, voice changes, and shortness of breath. If the side
effects are too bothersome the intensity of the shock can be decreased. The strength
of the pulses are adjusted gradually because of side effects, until the best results
are achieved.
Attacks
of epilepsy may be preceded by a feeling of unease or sensory discomfort called
an aura, which indicates the beginning of the seizure. Signs of an impending epileptic
seizure, which vary among patients, may include visual phenomena such as flickering
lights or "sunbursts."
If
a person with the vagus nerve stimulator senses an aura, a seizure coming on,
a magnet can be passed over the pacemaker. This activates the system and delivers
an extra dose of electricity possibly stop the seizure or cause it to be less
severe. The battery last between 3-5 years, after that time the generator has
to be removed and the batteries replaced.
The
vagus nerve stimulator is not a cure-all, but can be an important alternative
treatment for some people with uncontrolled seizures.This pacemaker is approved
for use with drugs or surgery in adults and children. This device does not help
everyone, but it does reduce the frequency and severity of seizures in many people.
Some people have even been able to decrease the amount of daily seizure medications,
which often has many side effects.