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In the Spotlight

February 24, 2000

Diabetic Foot Infections

By Adam Brochert M.D.
Personal MD.com Contributing Editor

 

Many of us choose to ignore our feet unless they are hurting us. For the diabetic, this would be a dangerous proposition. Diabetes is by far the number one cause of lower limb amputation in the absence of trauma. These amputations are often preceded by severe infections.

Why do people with diabetes develop foot infections?

The reasons people with diabetes tend to develop foot infections are multiple. Three main factors contribute. First is decreased sensation in the feet due to diabetic-induced nerve damage means that initial trauma and infection are not noticed as they would be in normal persons.

Second is poor blood flow from clogged arteries in the legs (smoking and diabetes are the two most potent risk factors for this condition, known as peripheral vascular disease). Without proper blood flow, the body cannot heal efficiently. Lastly, diabetes interferes with the function of white blood cells, the infection fighting cells of the body.

What can be done to prevent foot infections?

The most important aspect of diabetic foot infection treatment is prevention (see Diabetic Foot Care article) Once infection has set in, however, it is important to seek immediate medical attention. The sooner a physician is consulted, the higher the likelihood of avoiding the dreaded complication of gangrene, which generally requires amputation.

What are the signs of a foot infection?

The signs of infection are redness, increased temperature, pain (often absent in people with diabetes), swelling and loss of function (often not experienced by people with diabetes due to lack of sensation). With severe infection, pus or a blue/black color around the sight of infection may be seen. Often, diabetic foot infections are treated in a hospital setting.

How are foot infections treated?

The first principle of foot infection management is to avoid weight bearing. This may mean that your doctor will want you to stay in bed. While this can become frustrating after a while, it has been shown to improve outcome and prevent worsening of the infection.

Initial tests are usually ordered to assess the infection after your doctor examines you. This may include a number of different x-ray tests, ranging from a simple x-ray to computed tomography (CT) scan, magnetic resonance imaging (MRI) or other imaging studied.

These tests are painless and allow your doctor to know how extensive the infection is. Sometimes the infection extends into the bone, which requires prolonged antibiotic therapy (usually around six weeks). Routine blood tests are also ordered.

Antibiotics are then given and are an extremely important part of therapy. These are often given by the intravenous (I.V.) route, which means you will have to have an IV in your arm while you are in the hospital. Powerful antibiotics are required to treat these often-complicated infections.

Once antibiotics are given for several days, your doctor will need to assess whether therapy is working. If the infection progresses or does not improve, surgical intervention is usually required. This can take many forms.

Because of the many innovations in medical care over the last few decades, multiple efforts are usually undertaken to avoid limb amputation. Usually, the first surgical procedure is debridement. Debridement means that all non-living tissue is removed and the underlying tissue cleaned thoroughly.

This may even be done right away if the infection is severe. After debridement, the surgical wound is often left open to drain while antibiotics are continued. Daily (or more frequent) dressing changes are done as the patient continues to avoid weight bearing

If these measures are unsuccessful, amputation is often required. Amputation can range from partial toe resection to removing the bottom half of the leg. This is obviously the most feared complication of a diabetic foot infection.

Once the infection has resolved, whether through antibiotics or more severe measures, your doctor may want to assess the blood flow in your legs. There are different types of imaging studies available to look at blood flow, most of which are painless.

These measures are often important, as you may need a surgical bypass in your legs, much like those with heart attacks that need bypass surgery. If the arteries in your legs are clogged, a bypass may prevent severe foot infections in the future by allowing more blood to reach your legs.

Foot infections in the people with diabetes are common and in many cases, curable with antibiotic therapy. However, they can lead to one of the most feared complications of diabetes  amputation. A person with diabetes should seek immediate medical attention for any foot infection that occurs.

Copyright © 2000 PersonalMD.com. All rights reserved.

 

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