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In
the Spotlight
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| August
23, 2000 |
Colon Cancer:
Risk Factors And Diagnosis
By
Adam Brochert, M.D.
PersonalMD Medical Advisory Board
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Colon
cancer is the second leading cause of cancer death (behind
lung cancer) in the U. S., responsible for roughly 50,000
deaths per year. However, it seems to be discussed and
worried about much less than other cancers, such as breast
cancer. This is unfortunate, as screening tests have been
shown to reduce the chance of dying from colon cancer
by detecting it early, when cure is possible.
Early colon cancer causes no symptoms. The progression
from early pre-cancer changes to late-stage colon cancer
has been fairly well defined. Colon cancer almost always
starts out as a tiny bump on the inside lining of the
colon, called a polyp. After several years, the polyp
may grow and eventually turn into a cancer.
| In
at least 90 percent of cases, colon cancer occurs
in people older than 50 years. The following conditions
are thought to increase the risk of colon cancer:
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- Age
greater than 50 years;
- A
diet high in fat and low in fiber, fruits and
vegetables;
-
Cigarette smoking;
- Excessive
alcohol use;
- Lack
of exercise or sedentary lifestyle;
- A
family history of colon cancer;
- A
history of colon polyps or previous colon cancer;
- Inflammatory
bowel disease, a condition that causes irritation
of the bowels and other areas of the body for
unknown reasons;
- Certain
inherited conditions, such as a group of disorders
known as familial polyposis syndromes.
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| As
mentioned above, early colon cancer fails to cause
symptoms. When symptoms do occur, they may include: |
- Symptoms
of anemia or low blood counts, due to chronic
blood loss in the stool. Anemia can cause fatigue,
weakness, shortness of breath and lightheadedness;
- A
change in bowel habits, such as constipation or
a narrower width of the stool;
- Abdominal
swelling or cramps;
- Blood
in the stool.
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If colon cancer is suspected, several tests may be done.
A physical exam will include a rectal exam, which can
sometimes detect a low-lying cancer. The stool can also
be tested for tiny amounts of blood that cannot be seen.
Blood tests may be done to check for anemia or low blood
counts. An X-ray test called a barium enema may also be
done. This involves squirting dye through the anus and
up into the colon so that the inside of the colon can
be seen. The test usually used to confirm or check for
cancer in suspected cases is called Endoscopy. It's also
called Colonoscopy or Sigmoidoscopy. It uses a special
thin tube with a light and camera at the end of it. The
tube can be inserted into the anus and advanced up through
the colon. The inside of the colon can be seen with the
light and camera as the tube moves through the colon.
If any polyps or suspicious areas are seen, the tube can
also be used to take a sample of the area in question,
which is called as a biopsy.
If
cancer is detected, further X-ray tests may be done to
figure out if the cancer has spread into other areas of
the body. This often involves a CAT scan, which is a special
type of imaging test, of the abdomen and pelvis. Generally,
the only hope for cure is surgery to remove the cancer,
which is often successful. In some cases, radiation and/
or chemotherapy may be used in addition to the surgery.
Colon cancer can often be caught at an early, curable
stage with recommended screening tests. In those without
any risk factors for colon cancer, an annual rectal exam
is advised every year, starting at the age of 50 at the
latest. Endoscopy or barium enema is also advised every
five years starting at the age of 50 as well. Those who
have risk factors for colon cancer may be advised to start
screening at an earlier age and have the screening done
more often. Though these screening tests can be uncomfortable
and sometimes embarrassing, they can be life saving!
Anyone older than 50 years or with any of the above mentioned
risk factors for colon cancer is advised to speak with
his or her doctor, about colon cancer screening. Early
detection has been shown to reduce the risk of death from
this common cancer.
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