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In the Spotlight

November 8, 2000

Iron Deficiency Anemia: Signs And Symptoms


By Lee Phillips, M.D.

PersonalMD.com Medical Advisory Board

Anemia occurs when the amount of red blood cells or hemoglobin in the blood becomes low, causing the tissues of the body to be deprived of oxygen-rich blood. The blood of an anemic person has trouble carrying oxygen to tissues and organs, in a sense, become "starved" of oxygen and without oxygen, the tissues cannot produce energy to function.

There are several kinds of anemia, but the most common type of anemia, iron-deficiency anemia (IDA). Just as the name implies, it is due to insufficient iron in the body. 20 percent of all women of childbearing age have iron-deficiency anemia. The main cause of iron-deficiency anemia is blood lost during menses. During their reproductive years, women are more likely to develop iron deficiency because they lose 20-40 mg or iron per month during the menstrual cycle. Other common causes of anemia include: eating inadequate amounts of iron-rich foods, a deficiency of Vitamin B-12, a deficiency of folic acid, or poor iron absorption by the body.

How Much Iron Does A Woman Need?

The body recycles iron, so when a cell dies the iron is used to produce new cells. Due to the body's efficient reuse of iron, iron has a relatively small Recommended Daily Allowance (RDA). The RDA of iron for postmenopausal women is 10 milligrams; women of childbearing age as well as nursing mothers 15 milligrams, and pregnant women require 30 milligrams, and as many as 90 percent of women do not consume enough iron. An otherwise balanced diet may not supply ample iron to women in one of the following groups- menstruating, dieting, pregnant, and women who do not eat red-meat, as well as women who have trouble absorbing iron from their foods.

Red blood cells are formed in the bone marrow where iron-rich hemoglobin is stored. The heart pumps blood to the lungs, where the red blood cells bind to oxygen and this oxygen-rich blood circulates through the body to the tissues and organs. Red blood cells have a lifetime of 120 days and must constantly be replaced. Since hemoglobin is the main component of red blood cells, anemia occurs when the hemoglobin supply is inadequate. The initial stages of anemia normally present no symptoms. As the body's store of iron becomes exhausted, the body is not able to produce healthy red blood cells. If iron stores are not replenished, iron-deficiency anemia develops. It can take months or even years to develop symptoms of iron-deficiency anemia, symptoms include- weakness, paleness, shortness of breath and poor appetite.

How Is Anemia Diagnosed?

Anemia is diagnosed by a blood test, either by a finger stick in a clinic, or by a blood test done in a laboratory. Mild anemia does not have any significant long-term consequences. However, as the anemia becomes more severe, there are medical problems, which may arise. The most serious of these involve the heart. Severe anemia may cause a condition called high-output heart failure, where the heart must work harder to provide enough oxygen to the body. The heart beats faster and increases the amount of blood that is pumped per minute. When this condition occurs in individuals that have existing heart disease, the heart may be unable to keep up with this increased demand, and symptoms such as difficulty in breathing and swelling of legs can occur. Individuals who have coronary artery disease, or narrowing of the blood vessels supplying blood to the heart, may develop symptoms of angina, the pain associated with an insufficient blood flow to the heart muscle. Depending on the age of the woman and the degree of coronary artery disease, angina may develop with even mild anemia. In severe cases, the heart muscle may be permanently injured, and the woman will be at increased risk for a heart attack.

Finding the cause of the anemia is essential because the treatment changes with the cause. Most adolescent girls and women do not require iron supplements, but a diet high in iron-rich foods. When increasing diet alone cannot reverse iron deficiency, iron supplements may be needed. Where iron deficiency is caused by blood loss, stopping the blood loss will control the anemia.



  

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