IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

MEDROXYPROGESTERONE ACETATE - INJECTION (CONTRACEPTIVE)

(meh-DROX-ee-pro-JESS-tur-own A-seh-tate)

COMMON BRAND NAME(S): Depo-Provera Contraceptive

USES: This medication prevents ovulation resulting in a contraceptive effect. It is used to prevent pregnancy in women.

HOW TO USE: This medication is given by injection into a muscle usually once every 3 months.

SIDE EFFECTS: This medication causes irregular menstrual bleeding patterns but with continued use may result in an absence of menstrual bleeding. Headache, stomach cramps, dizziness, nausea, depression, breast tenderness, fluid retention, bloating, hot flashes, acne, change in appetite, sweating, weight gain, change in sexual desire or pain and irritation at the injection site may occur. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if you develop: a sudden severe headache, vomiting, fainting, pain in the calf associated with warmth/red- ness/swelling, breathing trouble, chest pain, vision changes, numbness in arms or legs. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor if you have: liver disease, diabetes, seizure disorders, kidney disease, heart trouble, eye problems, asthma, a history of depression, migraines, blood clots, miscarriage, breast cancer, any allergies. This medication must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. This medication is excreted into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: This medication can alter the effects of other medications. Tell your doctor of any over-the-counter or prescription medication you may take. This medication can alter results of certain laboratory tests. Remind your doctor you are taking this medication if you are scheduled for any lab tests. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately.

NOTES: A physical exam including a breast exam, pelvic exam and a pap smear will be done prior to starting this medication.

MISSED DOSE: It is important to take each dose as scheduled. If you miss a dose, contact your doctor to establish a new dosing schedule.

STORAGE: Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from heat and light. Do not store in the bathroom.

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Copyright 2004 by First DataBank, Inc.